Principal Medicinal Chemist

We are seeking a Principal Medicinal Chemist to lead and advance small-molecule drug discovery programs from early hit identification through development candidate selection. Requirements - PhD in Organic Chemistry or a related field with 3-8 years of industry experience (or MS with 5-10 years, BS with 8-15 years) in medicinal chemistry - Proven track record of advancing drug discovery programs through key milestones (Hit-to-Lead and Lead Optimization) - Deep expertise in synthetic organic chemistry, including modern methods and reaction mechanisms - Strong experience in structure-based and ligand-based drug design - Demonstrated ability to optimize compounds for potency, selectivity, and DMPK/safety properties - High level of creativity, productivity, and independent problem-solving ability - Experience managing external CROs and collaborating across disciplines - Excellent English communication skills with the ability to clearly present complex scientific concepts - Experience working remotely with international teams