Sr. Manager, Business Operations

At H1, we believe access to the best healthcare information is a basic human right. Our mission is to provide a platform that can optimally inform every doctor interaction globally. This promotes health equity and builds needed trust in healthcare systems. To accomplish this our teams harness the power of data and AI-technology to unlock groundbreaking medical insights and convert those insights into action that result in optimal patient outcomes and accelerates an equitable and inclusive drug development lifecycle. Visit h1.co to learn more about us.

What You’ll Do At H1

H1 is hiring a Sr. Manager, Business Operations to work directly alongside our CEO and COO in a highly visible, project leadership capacity. This is a high-trust role for someone who is sharp, polished, and wants to be in the room where things happen. You will be a force multiplier for executive leadership — picking up strategic projects, managing key external relationships, building board-level materials, and doing the work that keeps our executive team moving at speed. The role formally reports to our COO and will work extensively with our CEO.

You will:

• Own and project-manage strategic initiatives on behalf of the CEO and COO
• Build polished, board-ready materials independently — presentations, Excel models, briefing docs, and one-pagers for internal and external audiences
• Manage relationships with external partners, startups, and advisors in coordination with the CEO and COO — serving as a trusted, front-facing point of contact
• Travel on short notice occasionally when needed — representing H1 at partner meetings, and industry events
• Contribute to board preparation, company planning, and executive communications
• Help build culture, company events, and ad hoc initiatives that the CEO and COO need driven
• Step into whatever is most urgent — this role's value is in its flexibility and judgment

About You

You are someone with a strong management consulting skillset , and have experience in a high-performance environment — you know what a good presentation looks like, you are fast and fluent in Excel, manage stakeholders and projects effectively, and you can hold your own in a room with senior executives and external partners. You have the ambition and work ethic to earn the trust of a CEO and COO and the judgment to act on it.

• You have a consulting mindset: structured thinking, clean output, high standards for how work gets presented
• You are client-facing and polished — you can represent H1 externally with confidence
• You move fast, communicate proactively, and learn effectively from feedback during the process
• Willing and able to travel occasionally on short notice

Requirements

• 4+ years of experience in management consulting, investment banking, corporate strategy, or a high-growth startup in a business operations or chief of staff capacity
• Exceptional PowerPoint and Excel skills — able to produce polished, board-ready deliverables independently and quickly
• Demonstrated ability to manage external relationships with professionalism and discretion
• Comfortable operating close to senior leadership in a fast-moving, ambiguous environment
• MBA preferred, but not required

Compensation

This role pays $160,000 to $185,000 per year, based on experience, in addition to equity.

Anticipated role close date: 06/20/2026

H1 OFFERS

• Full suite of health insurance options, in addition to generous paid time off
• Pre-planned company-wide wellness holidays
• Retirement options
• Health & charitable donation stipends
• Impactful Business Resource Groups
• Flexible work hours & the opportunity to work from anywhere
• The opportunity to work with leading biotech and life sciences companies in an innovative industry with a mission to improve healthcare around the globe

H1 is proud to be an equal opportunity employer that celebrates diversity and is committed to creating an inclusive workplace with equal opportunity for all applicants and teammates. Our goal is to recruit the most talented people from a diverse candidate pool regardless of race, color, ancestry, national origin, religion, disability, sex (including pregnancy), age, gender, gender identity, sexual orientation, marital status, veteran status, or any other characteristic protected by law.

H1 is committed to working with and providing access and reasonable accommodation to applicants with mental and/or physical disabilities. If you require an accommodation, please reach out to your recruiter once you've begun the interview process. All requests for accommodations are treated discreetly and confidentially, as practical and permitted by law.

We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.